or this way:
$builder = new \Phalcon\Mvc\Model\Query\Builder();
$builder
->from('App\Models\Users')
->where('name = :name: AND age < :age:', array('name' => 'John', 'age' => 30));
->getQuery()->execute();
or
User::query()->where("name = :name: and age < :age:")->bind(["name" => 'John', "age" => 30])->execute();